The euphemistic term "emergence" is often used in medicine to describe the evolutionary processes by which living systems acquire resistance to chemotherapy. The purpose of this meeting is to understand clinical resistance from the perspective that it is best understood, and therefore controlled, if we adopt an evolutionary perspective from the start.
Reflecting the importance of the different disciplines needed to tackle the problem of drug resistance, our invited speakers represent a wide range of methodological approaches.
With an emphasis on the relevance to past but also potential future clinical studies, speakers will address different aspects of the resistance problem. Topics for discussion include antibiotic discovery (JL), antibiotic stewardship in the clinic (JI), rapid pathogen diagnosis (DP), bioinformatics approaches to clinical resistance adaptation (TaLi), reduced-dose trials using malaria in vivo models (AR), in vitro models of resistance adaptation (MB) studied using ideas from systems biology (IG, TLu), in addition to theoretical, epidemiological modelling (CCC).
| Jon Iredell Sydney Medical School |
| Santiago Castillo Center for Genomic Sciences, UNAM |
| Tami Lieberman Harvard Medical School |
| Tim Lu MIT |
| David Perlin Rutgers NJ Medical School |
| Robert Beardmore University of Exeter |
The Center of Genomic Sciences (CCG) is located in the Morelos Campus of UNAM, in the north part of the city of Cuernavaca. Click here for directions on how to get to CCG.
From Taxqueña bus station in Mexico City:
Several bus companies operate routes to Cuernavaca. Buses run on average every 20 minutes and tickets cost around $70 pesos ($5.50USD / £3.50). They are modern, safe and come equipped with air conditioning, toilets, and a movie during the trip. When there is no traffic the trip takes around 1 hour.
To get to the Center of Genomic Sciences, take a bus to "Cuernavaca Centro" and get off in the roundabout "Paloma de la Paz" of Cuernavaca. Then you can either take bus 13 towards the University (ticket costs $6.50 pesos) or a taxi (price around $25 pesos). Click here to see the route from Paloma de la Paz to the University.
From Mexico City's international airport:
From the bus station at the Airport there is a non-stop coach to Casino de la Selva Terminal in Cuernavaca. Pullman de Morelos runs a service every half an hour for $175 pesos ($13USD / £8). When arriving at the last stop, you can take bus 13 towards the University from the opposite side of the street (ticket costs $6.50 pesos). A taxi from the terminal to the University should cost around $40 pesos ($3USD / £2).
The Mexico-Acapulco expressway south from Mexico City takes around one hour to get to Cuernavaca. The toll road costs $85 pesos ($6.50USD / £8) or there is a free road which is less well maintained and is primarily single-laned. Click here to see the route from Mexico City's International Airport to the Center of Genomic Sciences in Cuernavaca.
Participants should book their own accommodation. Cuernavaca fills up with visitors from Mexico City at weekends and holidays, and therefore offers a wide range of hotels: from budget B+Bs to boutique hotels. The following hotels are conveniently located at reasonable fares:
GS Cuernavaca (10-min taxi to the University - with great panoramic views!).
Posada Tlaltenango (Nice and quiet Hotel/Spa not far from the University).
Hostería Las Quintas (Colonial style, beautiful gardens and amazing breakfast!).
(although if you are still interested in attending, please email sbdr@mmems.org)
